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- Evidence-Based Emergency Medicine: Is excessive IV fluid administration really a cause of cerebral edema in patients with diabetic ketoacidosis?
- Does Therapeutic Hypothermia Reduce Neurologic Sequelae in Infants?
- How Do Probiotics Compare to Placebo in Treating Necrotizing Enterocolitis?
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"Evidence-Based Emergency Medicine: Is excessive IV fluid administration really a cause of cerebral edema in patients with diabetic ketoacidosis?"
J Hom et al recently published a study in the Annals of Emergency Medicine examining the evidence that excessive IV fluids administered in the ER are a cause of cerebral edema, which is the leading cause of death for patients with diabetic ketoacidosis. The authors searched the literature (including observational studies) to compile an evidence-based medicine review of these occurances. Three studies were included. In the end, the authors found little support for a strong association between cerebral edema and IV fluid use. Find the abstract and full reference at PubMed: http://www.ncbi.nlm.nih.gov/pubmed/18387706?dopt=Abstract. |